immunology & Biochemistry
Mohammad Shafi Mojadadi; Nastaran Zakeralhosseini; Azam Khosrogerdi; Mostafa Roshanzadeh; Ali Taj
Abstract
Introduction: The coronavirus epidemic has caused a lot of confusion and tension in the health, economic, and political systems of the world, and its impact on society has led the governments' policy to support the production of drugs and related vaccines, Therefore, this research was conducted to investigate ...
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Introduction: The coronavirus epidemic has caused a lot of confusion and tension in the health, economic, and political systems of the world, and its impact on society has led the governments' policy to support the production of drugs and related vaccines, Therefore, this research was conducted to investigate the findings of vaccination of people infected with covid-19 hospitalized in Vasei Sabzevar Hospital in 2022.
Materials and Methods: This cross-sectional descriptive study was conducted in the year 2022 at Sabzevar city. 3686 people were included in the study by available sampling method. Information was extracted from Sib system using a demographics questionnaire and checklist and analyzed with SPSS 26 software.
Results: The results showed that %64.7 people had not been vaccinated. The number of hospitalized unvaccinated people was about 1.8 times the number of vaccinated people. There was no significant difference between the number of hospitalized men and women according to the vaccination status (P=.38), although there was a significant difference in the age of people (P=.001). The frequency of diabetes was higher in the vaccinated population. There was no significant difference between the number of hospitalized men and women in terms of the number of doses received (p=0.23). Also, the mortality rate in non-vaccinated people was significantly higher and this difference was significant (P=0.017).
Conclusion: Vaccination reduces mortality and hospitalization rates, so encouraging this and proper planning to prepare vaccines in similar critical situations is recommended.
Mosareza Tadayyonfar; Mehdi Amadani; Ali Tajabadi; Yaser Tabaraee; Hossein Khosrojerdi
Volume 23, Issue 1 , May and June 2016, , Pages 14-20
Abstract
Background & Objectives: Pain after surgery, especially in appendectomy, is one of the most common causes of patients’ dissatisfaction. Regarding common side effects of existing analgesics, the researchers decided to replace conventional medicine for overcoming postoperative pain in such patients. ...
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Background & Objectives: Pain after surgery, especially in appendectomy, is one of the most common causes of patients’ dissatisfaction. Regarding common side effects of existing analgesics, the researchers decided to replace conventional medicine for overcoming postoperative pain in such patients. Therefore, the aim of this study is to compare the pain relief effects of diclofenac and promethazine in patients with appendectomy. Materials & Methodes: This triple blind clinical trial was performed on 60 patients of 49 -15 years old undergoing appendectomy in Shahid Doctor Beheshti Hospital of Sabzevar in 2012. Participants were selected by convenience sampling and randomly divided into two 30-cases groups of control and intervention, respectively received diclofenac promethazine by muscle depth injection in Dursuglutyal muscle. According to the standard numeric pain scale, the pain was investigated in the first hours after treatment. Data were analyzed using the Pearson chi-square test and SPSS version 18, and the level of significance was selected as 0.05. Results: The difference of postoperative pain relief was significant (P=0/018) between the two groups at a half an hour. The average amount of pain in half an hour after injection of diclofenac and promethazine were 5.04± 2.26 and 3.96 ± 1.33, respectively. Also, the average amount of pain in one hour after injection of diclofenac and promethazine were 4.59 ± 5/31 and 3.30 ± 1.33, respectively. However, the differences were not statistically significant (P = 0.177). Conclusion: Promethazine is of greater analgesic efficacy than diclofenac. Therefore, a basic planing is recommended for the use of phenothiazines instead of highly morbid analgesics like non -steroidal anti-inflammatory drugs.